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Research / Cancer Stem Cells, Proteasomes and Experimental Therapeutics

Frank Pajonk, M.D., Ph.D. 
Associate Professor Experimental Radiation Oncology

Dr. Pajonk was recruited to UCLA in 2005. He was previously head of the Clinical and Experimental Radiation Biology Research Section at the University Hospital Freiburg, Germany. Dr. Pajonk received his M.D. at the University Freiburg and his Ph.D. at the Universities of Freiburg, Germany and Bale , Switzerland . From 1998 to 1999 he joined the Department of Radiation Oncology at the David Geffen School of Medicine at UCLA as a PostDoc. In 2002 he received his habilitation and venia legendi from the University of Freiburg, Germany. Dr. Pajonk's research has two major focuses. First, modulating the radiation response of malignant cells using proteasome inhibitors and understanding the underlying mechanisms, which lead to radiosensitization. Second, cancer stem cells and their response to cytokines, radiation and chemotherapy.